The Zhitomirsky family () is a Jewish family originating from present-day Ukraine. The earliest known members of the family lived in Bakhmut and Mariupol. Their descendants moved to Taganrog, now part of Russia, where they became known as a "dynasty of academics" as many of them engaged in research.

Tree of notable family members Hirsch Tzvi Zhitomirsky (1813–1874), Hebrew poet Konstantin Israel Zhitomirsky (1863–1918), Yiddish scholar and pedagogue (son of Hirsch Tzvi) Grigory Zhitomirsky (1888–1935), lawyer (son of Konstantin Israel) Eugeniusz Żytomirski (1911–1975), Polish poet (son of Grigory) (1891–1942), mathematician (son of Konstantin Israel) Viktor Zhitomirsky (1894–1954), Soviet-Tajikistani epidemiologist (son of Konstantin Israel) Zinaida Zhitomirskaya (1918–1980), bibliographer and translator (daughter of Viktor) Konstantin Erastov (1939–1996), linguist and translator (son of Zinaida) Gitel Sinaiskaya (daughter of Hirsch Tzvi) (1893–1968), Soviet sculptor (son of Gitel)

Other notable relatives Viktor Zhitomirsky's wife, Emilia Minukhina, was a niece of the Russian-Siwss Hebrew bibliographer Menahem Mendel Slatkine.

Viktor Zhitomirsky's grandson, Alexander Borun, is married to the Russian linguist Anna Dybo.

Konstantin Erastov's first wife, Tatiana Tankhilevich, was a daughter of the Soviet historian .

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