Picco is a surname. Notable people with the surname include:
Costanzo Picco (1917–2009), Italian military officer and skier Ed Picco (born 1961), Canadian Nunavut politician Franco Picco (born 1955), former Italian rally raid biker Giandomenico Picco (1948–2024), Italian diplomat and former United Nations Assistant Secretary-General for Political Affairs Leonel Picco (born 1998), Argentine professional footballer Leonello Picco (1876–1921), Italian entomologist Maria Angela Picco (1867–1921), Italian Roman Catholic professed religious Pierre Picco (born 1988), French slalom canoer
See also
Picco (disambiguation)