The 2003 Buffalo Destroyers season was the 5th season for the franchise and the 5th in Buffalo, New York. They finished with a 5–11 record and failed to qualify for the playoffs.

Coaching Ron Selesky started his first season as head coach of the Destroyers.

Regular season schedule Week Date Opponent Home/Away Result 1 February 1 Grand Rapids Rampage Home L 36–54 2 February 9 Carolina Cobras Home W 44–16 3 February 14 Arizona Rattlers Home W 49–45 4 February 22 Georgia Force Away W 63–43 5 March 1 Chicago Rush Home L 13–40 6 March 8 Tampa Bay Storm Away L 27–52 7 March 14 San Jose SaberCats Away L 41–58 8 March 23 Las Vegas Gladiators Home L 32–50 9 March 30 Detroit Fury Home L 14–34 10 April 6 New York Dragons Away W 46–39 11 April 11 Orlando Predators Away L 23–66 12 April 18 Los Angeles Avengers Away L 14–65 13 April 26 Indiana Firebirds Home W 36–35 14 May 1 Detroit Fury Away L 48–50 15 May 11 New York Dragons Home L 30–49 16 May 18 Las Vegas Gladiators Away L 38–55

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