Sir James Sexton (1856–1938) was a British trade union leader and politician.
James or Jimmy Sexton may also refer to: James A. Sexton (1844–1899), American soldier, businessman and politician Jimmy Sexton (baseball) (born 1951), American baseball player Jimmy Sexton (sports agent) (born 1963), American sports agent James Sexton (attorney) (born 1972), American family law attorney Buck Sexton (James Buckman Sexton, born 1981), American radio and television talk show host, author and conservative political commentator