Yacoubi is a surname. Notable people with the surname include:
Ahmed Yacoubi (1928–1985), Moroccan painter and storyteller. Ala Yacoubi, Tunisian rapper Hichem Yacoubi (born 1964), Tunisian-born French actor Mohamed Ali Yacoubi (born 1990), Tunisian footballer Seifeddine Rezgui Yacoubi (1992–2015), Tunisian mass murderer Souad Yacoubi (born 1938), Tunisian politician