15q overgrowth syndrome is a rare partial autosomal trisomy/tetrasomy syndrome. The condition was first identified in a 2009 report.
Signs and symptoms Features of this condition include: Facial dysmorphism (long thin face, prominent forehead, down-slanting palpebral fissures, prominent nose with broad nasal bridge, and prominent chin) Overgrowth (pre- and post-natal) Renal anomalies (horseshoe kidney, renal agenesis, and hydronephrosis) Mild to severe learning difficulties Behavioural anomalies Macrocephaly and craniosynostosis may also be present.
Causes The cause of this condition is genetic but its origins are unclear. The condition may be inherited (fashion unknown) or not inherited.
References
Further reading
External links