Comacchio is a town and comune of Emilia Romagna, Italy.
Comacchio may also refer to:
Comacchio Cathedral, in the city of Comacchio Valli di Comacchio, a series of lagoons to the south of Comacchio US Comacchio Lidi, an Italian association football club in Comacchio Santo Rosario, Comacchio, a church in Comacchio Santa Maria in Aula Regia, Comacchio, a church in Comacchio Battle of Comacchio, 809 naval battle Comacchio War, (1708–1709) Roman Catholic Archdiocese of Ferrara-Comacchio Roman Catholic Diocese of Comacchio A frazione in Cuvio, a town and comune of Lombardy, Italy.