The 1988 Prairie View A&M Panthers football team represented Prairie View A&M University as a member of the Southwestern Athletic Conference (SWAC) during the 1988 NCAA Division I-AA football season. Led by head coach Haney Catchings in his first full-year as head coach, the Panthers compiled an overall record of 4–6 and a mark of 2–5 in conference play, and finished sixth in the SWAC.
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