Major Tom is a persona of David Bowie referenced in his songs.

Major Tom may also refer to:

Major Tom (Coming Home), a song by Peter Schilling Major Tom, a horse that appeared in the show Bluey Tom Mitford (1909–1945), British major killed in action in Burma during World War II Major Zero, also known as Major Tom, a character from the Metal Gear series Seeking Major Tom, a studio album by William Shatner

See also Major Thomas (disambiguation) Tom Major-Ball (1879–1962), British music hall and circus performer