Spilimbergo is a surname. Notable people with the surname include:
Irene di Spilimbergo (1538–1559), Italian painter and poet Jorge Enea Spilimbergo (1928–2004), Argentine politician and journalist Lino Enea Spilimbergo (1896–1964), Argentine painter and engraver
See also Spilimbergo, comune located in the Friuli-Venezia Giulia region, Italy