Husam is a given name and surname. Notable people with the name include:

Ahmed Husam (born 1995), Maldivian swimmer Husam Abu al-Bukhari, Egyptian activist, Islamic thinker, physician, and researcher Husam al-Din Timurtash (1105–1154), Artuqid emir of Mardin and ruler of Aleppo Husam Azzam (born 1975), Palestinian track and field athlete Husam Chadat (born 1966), Syrian-German actor and director Husam Musa (born 1959), Malaysian politician Husam Kamal (born 1996), Qatari footballer Husam Uddin Chowdhury Fultali (born 1974), Bangladeshi Islamic scholar and author Husam Zomlot (born 1973), Palestinian diplomat, academic and economist