LEF or Lef may refer to:

Arts and entertainment LEF (journal), a 1920s Soviet journal of aesthetics L.E.F., a 2006 album by Ferry Corsten Lef, Dutch title of Guts, a 1999 Dutch comedy film

Organizations LEF – For the New Generation, a political party in the Netherlands Leading Edge Forum, a British consulting company Legal Education Foundation, a British grant-making foundation Life Extension Foundation, now the Biomedical Research & Longevity Society, an American organization

Science and technology Library Exchange Format, an integrated circuit design format Luquillo Experimental Forest, a UNESCO Biosphere Reserve in Puerto Rico Lymphoid enhancer-binding factor 1, a protein in humans Other Lef Nosi (1877–1946), Albanian publisher, archivist, philologist, and ethnographer See also