Bettin is a shortening for betting. Notable people with the surname Bettin or de Bettin include:

Gianfranco Bettin (born 1955), Italian politician Giorgio de Bettin (born 1972), Italian ice hockey player Grietje Staffelt (née Bettin, born 1975), German politician Luigi de Bettin (fl. 1960s), Italian bobsleigh competitor Joël Bettin (born 1959), French canoeist Mauro Bettin (born 1968), Italian cyclist Max Bettin (fl. 1908), American Jew leader known for the Max Bettin House Val Bettin (1923–2021), American actor