Shilo is a surname. Notable people with the surname include:
Andrey Shilo (born 1976), Belarusian former footballer Maksim Shilo (born 1993), Belarusian footballer Margalit Shilo (born 1942), Israeli historian Moshe Shilo (1920–1990), Israeli aquatic microbiologist Ronen Shilo (born 1958), Israeli entrepreneur and software engineer Rostislav Shilo (1940–2016), Soviet and Russian director of the Novosibirsk Zoo and politician Shmuel Shilo (1929–2011), Israeli actor, director and producer