RDB may refer to:
Computing Amiga rigid disk block, describing partition information Oracle Rdb, a relational database product Relational database
Military Cordite RDB, an experimental form of explosive developed for use by the Royal Navy in World War I Kel-Tec RDB, a semi-automatic carbine chambered for 5.56×45mm NATO rounds
Other RDB (band) (RDB Rhythm Dhol Bass), a UK music production group Richard Doll Building, located in Oxford, England State Security Service (RDB), Serbian secret police R. D. Burman, Indian music composer Rang De Basanti, 2006 Indian film