The 1990 McNeese State Cowboys football team was an American football team that represented McNeese State University as a member of the Southland Conference (Southland) during the 1990 NCAA Division I-AA football season. In their first year under head coach Bobby Keasler, the team compiled an overall record of 5–6, with a mark of 4–2 in conference play, and finished second in the Southland.

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