Down in Mississippi may refer to:
Down in Mississippi, album by blues guitarist J. B. Lenoir and title song with Fred Below on drums Down in Mississippi, song performed by Jimmy Reed Down in Mississippi, song recorded by Pops Staples Down in Mississippi, a song recorded by Mavis Staples on her 2007 album We'll Never Turn Back, written by J. B. Lenoir Down in Mississippi (Up to No Good), a song by Sugarland Down in Mississippi a 2008 play by Carlyle Brown