Karayel is a surname of Turkish origin, meaning "northwest wind". Notable people with the surname include:

Bekir Karayel (born 1982), Turkish middle and long-distance runner Cebrail Karayel (born 1994), Turkish footballer Emre Karayel (born 1972), Turkish actor and TV presenter Fikri Karayel (born 1987), Turkish Cypriot rock singer and songwriter Öykü Karayel (born 1990), Turkish actress

See also Poyraz Karayel, Turkish drama television series Vestel Karayel, a surveillance, reconnaissance, and combat unmanned aerial vehicle