Loricariichthys microdon is a species of freshwater ray-finned fish belonging to the family Loricariidae, the suckermouth armored catfishes, and the subfamily Loricariinae, the mailed catfishes. This catfish is endemic to Guyana where it occurs in the basin of the Rupununi. This species reaches a maximum standard length of and is believed to be a facultative air-breather.
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