Berghofer is a surname. Notable people with the surname include:
Chuck Berghofer (born 1937), American jazz double bassist and electric bassist Clive Berghofer (born 1935), Australian property developer, politician and philanthropist Gabriele Berghofer (born 1963), Austrian Paralympic skier and athlete Mark Berghofer (born 1985), Australian international lawn bowler
See also Clive Berghofer Stadium, Toowoomba QIMR Berghofer, Brisbane