The following is a timeline of major events during the Myanmar civil war (2021–present), following the 2021 military coup d'état and protests. It was also a renewed intensity of the existing Myanmar conflict.

2021 January 25 Jaunary – A week before the coup d'etat, the Myanmar Army LIB 575 clashed with the Restoration Council of Shan State (RCSS) in Mong Pan Township. No casualties were reported. RCSS spokesperson, Oum Khur, claimed that the attack violated the Nationwide Ceasefire Agreement.

February

5 February – The MNDAA attempted to assassinate Bai Yingneng in an ambush against the Kokang Border Guard Forces. Although Bai was unharmed, 3 bodyguards and 9 civilians died.

9 February – According to RCSS major, Kham San, the junta attacked RCSS camps in Hsipaw Township.

22 February – The Tatmadaw junta attacked a base belonging to the Kachin Independence Army (KIA) Brigade 6, Battalion 9 in Muse District, Shan State.

March

11 March – The KIA attacked a military base near Sal Zin, Mohnyin District, triggering an airstrike from junta fighter jets.

12 March – The KIA attacked a military base in Mogaung Township, triggering a counterattack from the junta involving helicopters. Four children were injured in Nant Haing village. 14 March – Protestors in Hlaingthaya Township's Hlaing River Road, a major thoroughfare, set up cement and sandbag barriers. Approximately 200 soldiers under the command of Lieutenant Colonel Nyunt Win Swe of the Myanmar Army Yangon Command breached the barriers and kettled protestors, killing at least 65 people. 25 March – The KIA seized the military base of Alaw Bum near the town of Laiza during the Battle of Alaw Bum airbase. 27 March – The Karen National Liberation Army (KNLA) attacked a military base, killing 10 soldiers and taking others hostage in the first attack on the military since the protests began. 28 March – Dozens of protesters travel to Myanmar's border areas to enlist in and train under one of the country's many insurgent groups, elevating the risk of a countrywide civil war. The first day of openly armed resistance against the coup, when armed protesters in the town of Kalay fought back against soldiers and security forces attacking a protest camp, with clashes also taking place in villages in Kale township. 30 March – The Committee Representing Pyidaungsu Hluttaw proposed the formation of a "federal armed force" to combat the military. The Arakan Army (AA) threatened to end its ceasefire with the military should the latter "persist in massacring civilians". Protesters increasingly began arming themselves with homemade weapons such as guns in an attempt to defend themselves against attacks by the military. Simultaneously, clashes with soldiers and IED attacks against administrative buildings and police stations became more common as the trend of protesters using armed resistance rose.

April 4 April – Seven insurgent groups who were signatories to the Nationwide Ceasefire Agreement aligned themselves with the Committee Representing Pyidaungsu Hluttaw, including the All Burma Student Democratic Front and the Karen National Union. 8 April – Taze became another frequent site of clashes when protesters fought back against soldiers with hunting rifles and firebombs in a battle that resulted in 11 protesters' deaths. In the same day, the country had surpassed 600 deaths related to anti-coup protests since 1 February. 10 April – The Northern Alliance, comprising the Arakan Army, the Ta'ang National Liberation Army and the Myanmar National Democratic Alliance Army, attacked a police station in Naungmon, Shan State, killing at least 10 police officers. 11 April – Battle of Alaw Bum- the junta launched a counter-attack to recapture the Alaw Bum base from the KIA using airstrikes and ground troops but had to retreat amidst heavy casualties. 16 April – Pro-democracy politician Min Ko Naing announced the formation of the National Unity Government (NUG), with ethnic minority politicians in senior roles. Ousted leaders Aung San Suu Kyi and Win Myint retained their positions. Min Ko Naing also asked the international community for recognition over the junta. 26 April – The Chinland Defense Force (CDF) began an armed resistance in Mindat, Chin State. In response, the junta cut off food and water supplies and declared martial law. Fighting began when a group of demonstrators outside the town's Aung San statue requested the release of six of their arrested colleagues, when a soldier of the regime allegedly fired at someone, prompting protesters to react.

May 5 May – The National Unity Government declared the formation of an armed wing, the People's Defence Force (PDF), to protect its supporters from military junta attacks and as a first step towards a Federal Union Army. 23 May – The People's Defence Force clashed with the Tatmadaw in the town of Muse, killing at least 13 members of Myanmar's security forces. 26 May – Six Tatmadaw soldiers were killed in an ambush by the Chinland Defense Force in Hakha, Chin State. The Tatmadaw launched airstrikes in Kayin State in response to the Karen National Liberation Army's capture and scorching of a Tatmadaw military base. Members of the Karenni People's Defence Force (KPDF) in Kayah State also captured and destroyed several Tatmadaw outposts near the state capital of Loikaw. The second-in-command of the Shanni Nationalities Army, Major General Sao Khun Kyaw was assassinated by the Myanmar Army. 29 and 30 May – The Tatmadaw used artillery and helicopters to strike PDF and KPDF positions in Loikaw and Demoso. 30 May – The Kachin Independence Army joined the anti-coup People's Defence Force battling junta troops in Katha Township, killing eight regime soldiers. Fighting was also continuing in Putao, Hpakant and Momauk Township.

June

1 to 3 June – Fighting erupted in Myawaddy District in which the military and Karen Border Guard Force (BGF), battling against a combined force of Karen ethnic armed groups and PDF, had left dozens of junta troops killed. 5 June – Four villagers in Kyonpyaw Township, Ayeyarwady Region, were shot dead after locals confront junta troops with slingshots and homemade gas. Three resistance fighters died, and 40 civilians were arrested after three bomb explosions in Hakha, the capital of Chin State Junta detained villagers in Putao Township and NLD party officials in Bhamo. 6 June – Houses and a Catholic church in Dawngakar, Demoso Township were damaged by shelling. Junta troops loot local grocery stores in Mongpai; houses were set on fire afterward.

9 June – A Kani PDF ambush on the Monywa-Kalewa highway, carried out with mines and small arms, reportedly killed and wounded a total of 20 Tatmadaw junta troops. Heavy rains eventually made the rebels cease shooting. 22 June – Junta forces using armoured vehicles raided a safehouse of the PDF in Mandalay, detaining a number of fighters. 30 June – Junta released 2,296 detainees, including journalists and protestors. Most detainees released were arrested due to the protests and more than 4,000 prisoners remained detained from protest arrests.

July

2 July – Media reported that Myanmar security forces killed at least 25 people in a confrontation with opponents of the military junta in the central town of Tabayin.

7 July – Six PDF rebels from the Dawei Defense Team attempted to raid a school occupied by Pyusawhti militia in Yaungmaw Village, Dawei Township. Reinforcing Tatmadaw troops and police officers killed two rebels and repelled the attack after two hours. 19 to 30 July – Myanmar's healthcare system collapsed at the onset of a new wave of COVID-19 cases as oxygen supplies ran low. The junta restricted the private sale of oxygen tanks to prevent healthcare workers participating in civil disobedience from providing free care to other civilians. Protesting doctors were arrested by the junta after being lured out of hiding to treat "patients".

August

1 August – Min Aung Hlaing extended the state of emergency, saying it could last until August 2023 and named himself the new Prime Minister of Myanmar 3 August – The United States charged two Myanmar citizens over an alleged plot to hire hitmen and assassinate Kyaw Moe Tun, Myanmar's representative to the United Nations who defied the military coup earlier in 2021. The junta denied involvement. 5 August – Chin National Army (CNA) captured the final junta base in Thantlang, warning the remaining junta soldiers in the town to surrender. 11 August – Five people jumped from a four-story building in Botahtaung Township, Yangon to escape raiding junta soldiers. The raid came after suspicions about a series of blasts in downtown Yangon. 14 August – PDF members ambushed six Myanmar Police Force officers with pistols in a Yangon train. Four police officers died; The PDF seized 2 Type 56 rifles, a BA-94 submachine gun, and a G3 rifle. 16 August – Wa National Party chairman, Sai Pao Nup, resigned after pledging to cooperate with the military regime and welcoming the election announced by the junta. 20 August – 50 junta soldiers were reportedly killed in a series of landmine attacks by resistance fighters in Gangaw Township. 27 August – The Tatmadaw junta raided a Dawei PDF camp on the outskirts of Dawei City after a tip-off from an informant. Although the PDF did not suffer casualties, the Tatmadaw detained 20 villagers and destroyed an estimated 100,000,000 kyat of matériel.

September

7 September – The NUG declared a state emergency across the nation and launched a people's defensive war against the military junta. 10 September – At least 17 people have been killed during clashes between the military and resistance militia in Myin Thar village, Magway region. 14 September – The National Unity Government claimed that over 1700 junta soldiers had been killed and 630 wounded in fighting during the previous three months. 21 September – Over 40 junta soldiers were reported killed during firefights in Kayah State and the Sagaing Region on 19 September. At least 6 civilian fighters were also killed in the clashes. 22 September – It was reported that nearly 8,000 residents of Thantlang town, Chin state, fled to Mizoram, India after houses were set ablaze by the junta army. 27 September – Over 30 junta soldiers and at least 14 civilian resistance fighters were reported killed in clashes over the previous weekend in several townships in Sagaing Region and Chin and Kayah States. 28 September – At least 20 junta soldiers were reported killed in ambushes in Shan state. At least 4 resistance fighters died in the clashes, along with an unarmed 70-year-old civilian.

October

6 October – Over 40 junta soldiers were killed in ambushes in Gangaw Township, Magwe Region. 7 October – Junta controlled media reported at least 406 junta informants had been killed and 285 wounded since 1 February in targeted attacks by resistance forces. The same day, Brigadier-General Phyo Thant, a senior commander of the North-western junta forces was reportedly detained after allegedly contacting resistance forces with the intention to defect, making him the highest-ranking official to have attempted to defect so far. 11 October – Around 90 junta soldiers were reported killed in clashes in the Sagaing and Magwe regions, and Kayah State in fighting over the previous weekend.

November

16 November – Junta forces overrun a Kalay PDF base in Kalay. They captured 9 Kalay PDF medics and killed 2 PDF fighters from the Kalay PDF Battalion 3. 17 November – Junta forces ambushed and captured an outpost of the Moebye PDF in southern Shan State's Pekhon Township. The PDF fighters guarding the outpost were asleep when a military unit from Light Infantry Battalion (LIB) 422, surrounded the fighters and began their ambush. The fighters had to retreat from the outpost.