Sepehr (Persian: سپهر) is a Persian masculine given name and a surname. It means celestial sphere. Notable people with the name include:
Given name Sepehr Heydari (born 1980), Iranian football player Sepehr Mohammadi (born 1989), Iranian futsal player Sepehr Salimi (born 1981), Iranian blogger and activist
Surname Ahmad Ali Sepehr (1889–1976), Iranian historian and politician Mohammad Taqi Sepehr (1801–1880), Iranian court historian
See also Shahin & Sepehr, Iranian-American guitarist duo Sepehr (disambiguation)