Buff is the surname of:
Aaron Buff (1911–1994), American chair-maker Charlotte Buff (1753–1828), youthful acquaintance of the German polymath Goethe, who fell in love with her Conrad Buff II (1886–1975), Swiss-born American co-creator of illustrated children's books Conrad Buff III (1926–1989), American architect, son of the above Conrad Buff IV (born 1948), American film editor, son of the above Evelyn Buff-Segal (1913–2000), née Buff, American abstract expressionist painter Joe Buff, American author of naval techno-thrillers Johnny Buff (1889–1955), American boxer Oliver Buff (born 1992), Swiss footballer Sebastian Buff (1828–1880), Swiss portrait painter Wade Buff, a member of the 1950s The Dream Weavers vocal group Xavier Buff (born 1971), French mathematician