Lefebre, Lefèbre, LeFebre, or Le Febre is a common surname, related to the French surname Lefebvre. Notable people with this surname include:
Valentin Lefebre (1637–1677), Flemish painter, draughtsman and printmaker Edward A. Lefebre (1834–1911), American virtuosic saxophonist Joseph Oscar Lefebre Boulanger (1888–1958), Canadian politician and lawyer Bobby LeFebre (born 1982), American poet
See also Lefèvre Lefébure