CAMSAP1

Calmodulin-regulated spectrin-associated protein 1 (CAMSAP1) is a human protein encoded by the gene CAMSAP1. Like other CAMSAP-family proteins, it is a microtubule minus-end anchor, and binds microtubules through its CKK domain.

Clinical significance CAMSAP1 is vital for neuron polarisation, and so mice that lack CAMSAP1 die of epileptic seizures.

See also

CAMSAP2 CAMSAP3

References