Birtwell is a surname. Notable people with the surname include:
Alec Birtwell (1908–1974), English cricketer Celia Birtwell (born 1941), British textile and fashion designer Ian Birtwell (born 1944), English rugby player and coach S. A. Birtwell (–1897), English vegetarianism activist
See also Andrena birtwelli, also known as the Birtwell's miner bee, a species of miner bee Bertwell, an unincorporated community in Saskatchewan, Canada