Klouček is a surname of Czech origin. Notable people with this surname include:
Celda Klouček (Celestýn Klouček) (1855–1935), Czech schulptor and palaeontologist Josef Klouček (1905–1987), Czech skier, competitor in the 1928 Winter Olympics (military patrol) Tomáš Klouček (1980–2025), Czech ice hockey player
See also Frank Kloucek (born 1956), Democrat politician from South Dakota, US