Mbewe is a surname of Zambian origin. Notable people with the surname include: Agripa Mbewe (born 1987), retired Zambian football striker Ernest Mbewe (born 1994), Zambian footballer Festus Mbewe (born 1988), Zambian footballer Mary Mbewe, Zambian journalist Tsakane Mbewe (born 1987), South African netball player