Serapio may refer to:
Ancient history Publius Cornelius Scipio Nasica Serapio (182/181–132 BC), Ancient Roman politician
Modern history Surname Antonio Serapio, Philippine lawmaker Kevin Serapio, Nicaraguan football player Given name José Serapio Palimino Gomez, better known as "Pepper Gomez", American wrestler and bodybuilder Serapio Bwemi Magambo, Ugandan priest Serapio Calderón, Peruvian interim president Serapio Reyes Ortiz, ninth Vice-President of Bolivia Serapio Rukundo, Ugandan politician
See also Serapion (disambiguation) Seraphin (disambiguation)