Shafir is a surname. Notable people with the surname include:
Eldar Shafir, American behavioral scientist Herzl Shafir (1929–2021), Israeli major general Iakov Mikhailovich Shafir (1886–1938), Bolshevik historian Iakov Moiseyevich Shafir (1887–1938), Soviet investigator and journalist Marina Shafir (born 1988), Moldovan wrestler and mixed martial artist Michael Shafir (born 1944), Romanian–Israeli political scientist Relik Shafir (born 1953), Israeli brigadier general Shlomo Shafir (1924–2013), Israeli journalist and historian