Charlotte Thompson may refer to:

Charlotte Pullein-Thompson (born 1957), author Charlotte Thompson-Edgar, British nurse Charlotte Thompson Reid (1913–2007), U.S. Congresswoman Charlotte Thompson (actress) (1843-1898), English actress Charlotte Thompson (playwright) (1884–1919), American playwright; adapter of Rebecca of Sunnybrook Farm

See also Charlotte Small (1785–1857), wife of explorer David Thompson