L'Huillier may refer to:

Anne L'Huillier (born 1958), French physicist Jean-Philippe L'Huillier (born 1951), Swiss sailor Peter L'Huillier (1926–2007), scholar of canon law and archbishop of the Orthodox Church in America Simon Antoine Jean L'Huilier (or L'Huillier) (1750–1840), Swiss mathematician Fort L'Huillier (sometimes spelled Le Hillier), a short-lived fortification in New France