Pequeno or Pequeño is a Portuguese surname, a nickname for a small person, from Portuguese pequeno, Spanish pequeño "small". Notable people with the surname include: Gué Pequeno (1980), Italian rapper and record producer Nilton Pequeno (1998), Santomean footballer Paula Pequeno (1976), Brazilian volleyball player Vavá Pequeno (1994), São Toméan footballer Walisson Pequeno (1999), Brazilian footballer