Paustian is a German language surname. It stems from the male given name Sebastian. Notable people with the surname include:
Matthias O. Paustian, German economist Ole Paustian (born 1937), Danish rower Peter Paustian, German rower Ross Paustian (born 1956), American politician Samantha Paustian-Underdahl, American psychologist Timothy D. Paustian, American microbiologist
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