The 2021–22 Slovak Cup was the 53rd edition of the football competition.
Slovan Bratislava were the defending champions, defeating Žilina in the 2021 final.
Slovan Bratislava managed to advance to the final again, but were defeated by their rivals Spartak Trnava.
Spartak Trnava earned automatic qualification for the UEFA Europa Conference League second qualifying round.
Format The Slovak Cup is played as a knockout tournament. All matches that end up as a draw after 90 minutes are decided by penalty shoot-outs. All rounds are played as one-off matches except the semi-finals, which are played over two legs.
Preliminary round
!colspan="3" align="center"|18 July 2021
!colspan="3" align="center"|24 July 2021
!colspan="3" align="center"|25 July 2021
!colspan="3" align="center"|28 July 2021
!colspan="3" align="center"|29 July 2021
First round
!colspan="3" align="center"|30 July 2021
!colspan="3" align="center"|31 July 2021
!colspan="3" align="center"|1 August 2021
!colspan="3" align="center"|3 August 2021
!colspan="3" align="center"|4 August 2021
!colspan="3" align="center"|5 August 2021
!colspan="3" align="center"|11 August 2021
Second round
!colspan="3" align="center"|18 August 2021
!colspan="3" align="center"|24 August 2021
!colspan="3" align="center"|25 August 2021
!colspan="3" align="center"|1 September 2021
!colspan="3" align="center"|4 September 2021
!colspan="3" align="center"|22 September 2021
Third round
!colspan="3" align="center"|14 September 2021
!colspan="3" align="center"|15 September 2021
!colspan="3" align="center"|21 September 2021
!colspan="3" align="center"|22 September 2021
!colspan="3" align="center"|28 September 2021
!colspan="3" align="center"|29 September 2021
!colspan="3" align="center"|6 October 2021
!colspan="3" align="center"|9 October 2021
Fourth round The draw for the fourth round was held on 7 October 2021.
!colspan="3" align="center"|19 October 2021
!colspan="3" align="center"|20 October 2021
!colspan="3" align="center"|26 October 2021
!colspan="3" align="center"|27 October 2021
!colspan="3" align="center"|2 November 2021
!colspan="3" align="center"|3 November 2021
!colspan="3" align="center"|10 November 2021
!colspan="3" align="center"|21 November 2021
!colspan="3" align="center"|12 February 2022
!colspan="3" align="center"|15 February 2022
Round of 16 The draw for the round of 16 was held on 2 December 2021.
!colspan="3" align="center"|1 March 2022
!colspan="3" align="center"|2 March 2022
!colspan="3" align="center"|9 March 2022
Quarter-finals The draw for the quarter-finals was held on 3 March 2022.
Semi-finals The draw for the semi-finals took place on 18 March 2022.
First leg
Second leg
Final
See also 2021–22 Slovak First Football League 2022–23 UEFA Europa Conference League
References
External links Slovak Cup at Futbalnet.sk Slovak Cup at Soccerway.com