Jean-Nicolas is a French compound given name, a combination of Jean and Nicolas. Notable people with the name include:
Jean-Nicolas Bouilly (1763–1842), French playwright, librettist and politician Jean-Nicolas Boulay (1837–1905), French clergyman, bryologist and paleobotanist Jean-Nicolas Carrière (born 1985), Canadian football player Jean-Nicolas Corvisart (1755–1821), French physician Jean-Nicolas Curély (1774–1827), French cavalry officer Jean-Nicolas Céré (1737–1810), French botanist and agronomist Jean-Nicolas Démeunier (1751–1814), French writer and politician Jean-Nicolas de Francine (1662–1735), French musician Jean-Nicolas Gannal (1791–1852), French chemist Jean-Nicolas Geoffroy (1633–1694), French harpsichordist, organist and composer Jean-Nicolas Huyot (1780–1840), French architect Jean-Nicolas Laverlochère (1812–1884), French Roman Catholic missionary in Canada Jean-Nicolas Lemmens (1850–1897), Dutch Catholic bishop Jean-Nicolas Marjolin (1780–1850), French surgeon and pathologist Jean-Nicolas Marrigues (1757–1834), French organist Jean-Nicolas Pache (1746–1823), French politician Jean-Nicolas Nissage Saget (1810–1880), President of Haiti Jean-Nicolas Stofflet (1753–1796), French military leader Jean-Nicolas Trouille (1750–1825) was a French architect, engineer and politician