Gushue is a surname. Notable people with the surname include:
Brad Gushue (born 1980), Canadian curler George W. Gushue (1854–1941), Newfoundland politician Joe Gushue (1915–1996), American referee Raymond Gushue (1900–1980), Canadian lawyer and academic administrator from Newfoundland Taylor Gushue (born 1993), American baseball player