Escalante may refer to:
People Amat Escalante (born 1979), Mexican filmmaker Bernardino de Escalante (1537–after 1605), 16th-century Spanish writer, author of one of the first European books on China Enrique Escalante (born 1984), Puerto Rican volleyball player Francis García Escalante, Mexican transvestite who has become a famous actor Gonzalo Escalante (born 1993), Argentine footballer Jaime Escalante (1930–2010), Bolivian former mathematics teacher Joe Escalante (born 1963), American musician Jorge Volpi (born 1968), Mexican writer José Escalante (born 1995), Honduran footballer Silvestre Vélez de Escalante, Spanish padre and explorer in North America
Places United States The Escalante, a hotel in Ash Fork, Arizona Escalante, Utah Escalante Butte, of Eastern Grand Canyon Escalante Creek, Colorado Escalante Desert, Utah Escalante River, Utah Grand Staircase–Escalante National Monument, Utah Escalante National Monument, Utah
Elsewhere Escalante Department, an administrative district in Argentina Escalante (El Apagado), a volcano in Chile Escalante, Negros Occidental, Philippines Escalante, Cantabria, Spain Escalante River (Venezuela) 5095 Escalante, an asteroid Escalante (Martian crater), a crater on Mars
Other uses Escalante massacre, 1985 in Escalante, Negros Occidental, Philippines Escalante syndrome or Fragile X Syndrome, a genetic disorder