The 2021–22 Lafayette Leopards men's basketball team represented Lafayette College in the 2021–22 NCAA Division I men's basketball season. The Leopards, led by 27th-year head coach Fran O'Hanlon, played their home games at the Kirby Sports Center in Easton, Pennsylvania as members of the Patriot League.
The Leopards finished the season 10–20, 7–11 in Patriot League play, to finish in a tie for seventh place. In the Patriot League tournament, they were defeated in overtime by Bucknell in the first round. During the season, on January 21, longtime head coach Fran O'Hanlon announced that he would retire at the end of the season, ending his 27-year run as the head coach. On March 29, Colgate assistant Mike Jordan was named as O'Hanlon's successor.
Previous season In a season limited due to the ongoing COVID-19 pandemic, the Leopards finished the 2020–21 season 9–6, 9–5 in Patriot League play, to finish in first place in the Central Division. As the No. 3 seed in the Patriot League tournament, they were upset by Bucknell in the quarterfinals.
Roster
Schedule and results
!colspan=12 style=| Non-conference regular season
!colspan=12 style=| Patriot League regular season
!colspan=9 style=| Patriot League tournament
Sources:
References