There were a number of medieval rabbinic scholars and biblical exegetes named Ephraim:
Ephraim ben Isaac of Regensburg, a 12th-century German tosafist Ephraim ben Jacob HaKohen, a 17th-century Lithuanian talmudist Ephraim ben Joseph of Chelm, a 16th-century Polish liturgist Ephraim ben Judah, a 12th-century French liturgist Ephraim ben Nathan, a 13th-century German talmudist Ephraim ben Samson, a 12th-century French tosafist Ephraim of Bonn, a 12th-century German talmudist Ephraim of Sudilkov, an 18th-century Polish author and member of the Baal Shem Tov's rabbinic dynasty