Popek is a Polish surname. Notable people with the surname include:
Edward Popek (1919–2001), American flying ace
Gerald J. Popek (1946–2008), American computer scientist
Jacek Popek (born 1978), Polish football player Mark Popek (born 1990), American football player Tadeusz Popek (1915–1942), World War II Polish resistance member
See also Popek (born 1978), Polish rapper and mixed martial arts fighter Popeck (born 1936), French comedian