Misick is a surname. Notable people with the surname include:
Ariel Misick (born 1951), Turks and Caicos Islands politician Emmanuel Misick, Turks and Caicos Islands politician Michael Misick (born 1966), Premier of the Turks and Caicos Islands Washington Misick (born 1950), Premier of the Turks and Caicos Islands
See also Gladys Carlyon De Courcy Misick Morrell (1888–1969), Bermudian suffragette leader Missick