Paula Badosa defeated Victoria Azarenka in the final, 7–6(7–5), 2–6, 7–6(7–2) to win the women's singles tennis title at the 2021 Indian Wells Masters. It was her first WTA 1000 title and second career WTA Tour singles title. Badosa was the first Spanish woman to win the title. Azarenka was aiming to become the first woman to win the title three times. At three hours and four minutes, it was the longest-ever Indian Wells women's final.

Bianca Andreescu was the defending champion from when the tournament was last held in 2019, but lost in the third round to Anett Kontaveit. Two-time champion Kim Clijsters made her return to the event for the first time since 2011; she lost in the first round to Kateřina Siniaková. Lucky loser Beatriz Haddad Maia became the first Brazilian woman to defeat a player ranked in the world's top three, defeating world No. 3 Karolína Plíšková in the third round. By reaching the semifinals, Ons Jabeur became the first Arab player to enter the top 10 of the world rankings.

Seeds All seeds receive a bye into the second round.

Draw

Finals

Top half

Section 1

Section 2

Section 3

Section 4

Bottom half

Section 5

Section 6

Section 7

Section 8

Qualifying

Seeds

Qualifiers

Lucky losers

Qualifying draw

First qualifier

Second qualifier

Third qualifier

Fourth qualifier

Fifth qualifier

Sixth qualifier

Seventh qualifier

Eighth qualifier

Ninth qualifier

Tenth qualifier

Eleventh qualifier

Twelfth qualifier

References

External links Main draw Qualifying draw