Guinot is a surname. Notable people with the surname include:

Bernard Guinot (1925–2017), French astronomer Danièle Guinot (born 1933), French biologist Eugène Guinot (1805–1861), French journalist, writer, and playwright Luis Guinot (1935–2022), American diplomat Maria Guinot (1945–2018), Portuguese singer

See also Masters Guinot-Mary Cohr