Lewis Cass (1782–1866), was an American military officer, politician, and statesman
Lewis Cass may also refer to:
People Lewis Cass Jr. (1814–1878), American diplomat, and son of the politician Lewis Cass Hunt (1824–1886), American army general Lewis Cass Ledyard (1852–1932), American lawyer Lewis Cass (footballer) (born 2000), English footballer
Places Lewis Cass High School, high school in Walton, Indiana Lewis Cass Tech, public high school in Midtown Detroit, Michigan Lewis Cass Building, former name of Elliott-Larsen Building, state government building in Lansing Michigan
Other Lewis Cass expedition, 1820 survey of Michigan territory