Alex de Minaur was the reigning champion from when the tournament was last held in 2019, but chose not to participate this year.
John Isner won his sixth Atlanta Open title, defeating Brandon Nakashima in the final, 7–6(10–8), 7–5.
Seeds The top four seeds receive a bye into the second round.
Draw
Finals
Top half
Bottom half
Qualifying
Seeds
Qualifiers
Qualifying draw
First qualifier
Second qualifier
Third qualifier
Fourth qualifier
References
External links Main draw Qualifying draw