The 2000–01 Gamma Ethniki was the 18th season since the official establishment of the third tier of Greek football in 1982 and under the name Second Division (). Patraikos was crowned champion, thus winning promotion to Beta Ethniki. Chalkidona-Near East also won promotion after a winning a promotion play-off in which was participated with Atromitos and Ethnikos Piraeus.
Acharnaikos, Naoussa, Kozani, Ampelokipi, Lamia, Veria, Anagennisi Karditsa, ILTEX Lykoi, Pierikos and Ialysos were relegated to Delta Ethniki.
League table
Results
Promotion play-offs
Relegation play-off
Top scorers RankPlayerClubGoals1 Andreas AndroutsosPatraikos 352 Stavros LioftisApollon Krya Vrysi283 Dimitrios MoutasEthnikos Piraeus21 Michalis KlokidisLeonidio5 Stavros KomiotisEthnikos Piraeus17 Rastislav Ján LazoríkMarko
References