Human spaceflights were vital to the operation of Mir, allowing crews and equipment to be carried to and from the space station. Mir was visited by a total of 39 crewed missions, comprising 30 Soyuz flights (1 Soyuz-T, 29 Soyuz-TM) and 9 Space Shuttle flights. These missions carried both long-duration crew members flying principal expeditions (ranging from 70 days up to Valeri Polyakov's 14-month stay beginning in January 1994, which still holds the record for the longest continuous spaceflight by a single person) and short-term visitors (who spent about a week aboard the station). Many of the crew who visited Mir used different spacecraft to launch than they did to land; the first such examples were Aleksandr Viktorenko and Muhammed Faris who flew up in Soyuz TM-3 (launched 22 July 1987) and landed a week later in Soyuz TM-2 on 30 July 1987. The largest crew aboard Mir simultaneously (not including Shuttle-Mir missions) was 6, which first occurred with the launch of Soyuz TM-7 on 26 November 1988 and lasted for just over three weeks.

In this list, uncrewed visiting spacecraft are excluded (see List of uncrewed spaceflights to Mir for details), and long-duration crew members are listed in bold. Times are given in Coordinated Universal Time (UTC). "Time docked" refers to the spacecraft and does not necessarily correspond to the crew.

198619871988198919901991199219931994199519961997199819992000

{|class="wikitable sticky-header" style="font-size: 85%;" |- ! scope="col" |# ! scope="col" |Mission ! scope="col" |Launch date (UTC) ! scope="col" |Time docked ! scope="col" |Landing date (UTC) ! scope="col" |Launch crew ! scope="col" |Crew photo ! scope="col" |Crew patch ! scope="col" |Notes |- ! scope="row" |1. |align="center"|Soyuz T-15 |13 March 198612:33:09 |~52 days~20 days |16 July 198612:34:05 | Leonid Kizim Vladimir Solovyov

|Delivered the first crew, flying expedition EO-1, to Mir, then undocked, flew to and docked with Salyut 7 before returning to Mir. Remains the only spacecraft to have visited two space stations during one mission. |- ! scope="row" |2. |align="center"|Soyuz TM-2 |5 February 198721:38:16 |~172 days |30 July 198701:04:12 | Yuri Romanenko Aleksandr Laveykin

|Delivered the second crew, flying expedition EO-2, to Mir. |- ! scope="row" |3. |align="center"|Soyuz TM-3 |22 July 198701:59:17 |~158 days |29 December 198709:16:15 | Aleksandr Aleksandrov Aleksandr Viktorenko Muhammed Faris

|Delivered a third crew member, Aleksandrov, for EO-2, as well as the first Mir Intercosmos mission, EP-1, to the station. The EP-1 crew members, Viktorenko and Faris, returned to Earth aboard Soyuz TM-2 after 8 days. |- ! scope="row" |4. |align="center"|Soyuz TM-4 |21 December 198711:18:03 |~177 days |17 June 198810:12:32 | Vladimir Titov Musa Manarov Anatoli Levchenko

|Delivered the third expedition crew, EO-3, to Mir, in addition to Anatoli Levchenko, who returned to Earth aboard Soyuz TM-3 with the returning EO-2 crewmembers after 8 days. |- ! scope="row" |5. |align="center"|Soyuz TM-5 |7 June 198814:03:13 |~90 days |7 September 198800:49:38 | Anatoly Solovyev Viktor Savinykh Aleksandr Aleksandrov

|Delivered the second Mir Intercosmos mission, EP-2, to the station. All three crew returned to Earth aboard Soyuz TM-4 after 10 days. |- ! scope="row" |6. |align="center"|Soyuz TM-6 |29 August 198804:23:11 |~112 days |21 December 198809:57:00 | Valeri Polyakov Vladimir Lyakhov Abdul Ahad Mohmand

|Delivered a third crew member, Polyakov, for EO-3, in addition to the third Mir Intercosmos crew, EP-3, who returned to Earth aboard Soyuz TM-5 after 9 days. |- ! scope="row" |7. |align="center"|Soyuz TM-7 |26 November 198815:49:34 |~149 days |27 April 198902:57:58 | Aleksandr Volkov Sergei Krikalev Jean-Loup Chrétien

|Delivered the EO-4 and Aragatz crews to Mir, with Chrétien returning to Earth aboard Soyuz TM-6 after 25 days. |- ! scope="row" |8. |align="center"|Soyuz TM-8 |5 September 198921:38:03 |~165 days |19 February 199004:36:18 | Aleksandr Viktorenko Aleksandr Serebrov

|Delivered the EO-5 crew to Mir. |- ! scope="row" |9. |align="center"|Soyuz TM-9 |11 February 199006:16:00 |~177 days |9 August 199007:33:57 | Anatoly Solovyev Aleksandr Balandin

|Delivered the EO-6 crew to Mir. |- ! scope="row" |10. |align="center"|Soyuz TM-10 |1 August 199009:32:21 |~129 days |10 December 199006:08:12 | Gennadi Manakov Gennady Strekalov

|Delivered the EO-7 crew to Mir. |- ! scope="row" |11. |align="center"|Soyuz TM-11 |1 December 199008:13:32 |~173 days |26 May 199110:04:13 | Viktor Afanasyev Musa Manarov Toyohiro Akiyama

|Delivered the EO-8 crew to Mir, in addition to the Japanese Kosmoreporter mission. Akiyama, who became the first Japanese citizen to fly in space, returned to Earth aboard Soyuz TM-10 after 8 days. |- ! scope="row" |12. |align="center"|Soyuz TM-12 |18 May 199112:50:28 |~142 days |10 October 199104:12:18 | Anatoly Artsebarsky / Sergei Krikalev Helen Sharman

|Delivered the EO-9 crew to Mir, in addition to the British Project Juno mission. Sharman, the first Briton to travel into space whilst not holding American citizenship, returned to Earth aboard Soyuz TM-11 after 8 days. |- ! scope="row" |13. |align="center"|Soyuz TM-13 |2 October 199105:59:38 |~173 days |25 March 199208:51:22 | Toktar Aubakirov Franz Viehböck

|The last crewed spaceflight ever launched by the Soviet Union, Soyuz TM-13 delivered a third crew member to Mir for EO-10, in addition to carrying the first Austrian to go into space as part of the Austromir '91 mission. Aubakirov and Viehböck returned to Earth aboard Soyuz TMA-12 after 8 days. |- ! scope="row" |14. |align="center"|Soyuz TM-14 |17 March 199210:54:30 |~143 days |10 August 199201:05:02 | Aleksandr Viktorenko Aleksandr Kaleri Klaus-Dietrich Flade

|The first crewed spaceflight to be launched by the Russian Federation, Soyuz TM-14 delivered the EO-11 crew to Mir, in addition to Flade, flying the German Mir '92 mission, who returned to Earth aboard Soyuz TM-13 after 8 days. |- ! scope="row" |15. |align="center"|Soyuz TM-15 |27 July 199206:08:42 |~187 days |1 February 199303:49:57 | Anatoly Solovyev Sergei Avdeyev Michel Tognini

|Delivered the EO-12 crew to Mir, in addition to the French Antarès mission. Tognini returned to Earth aboard Soyuz TM-14 after 14 days. |- ! scope="row" |16. |align="center"|Soyuz TM-16 |24 January 199305:58:05 |~177 days |22 July 199306:41:50 | Gennadi Manakov Aleksandr Poleshchuk

|Delivered the EO-13 crew to Mir. Became the only Soyuz spacecraft to dock at Kristalls distal APAS-89 port in order to check the port in preparation for the Shuttle-Mir flights which followed. |- ! scope="row" |17. |align="center"|Soyuz TM-17|1 July 199314:32:58 |~195 days |14 January 199408:18:20 | Vasili Tsibliyev Aleksandr Serebrov Jean-Pierre Haigneré

|Delivered the EO-14 crew to Mir, in addition to the French Altair mission. Haigneré returned to Earth aboard Soyuz TM-16 after 21 days. |- ! scope="row" |18. |align="center"|Soyuz TM-18|8 January 199410:05:34 |~180 days |9 July 199410:32:35 | Viktor Afanasyev Yury Usachev Valeri Polyakov| | |Delivered the EO-15 crew to Mir, with Polyakov remaining in space for over 437 days, the current world record for longest single spaceflight. |- ! scope="row" |19. |align="center"|Soyuz TM-19|1 July 199412:24:50 |~124 days |4 November 199411:18:26 | Yuri Malenchenko Talgat Musabayev| | |Delivered the EO-16 crew to Mir. |- ! scope="row" |20. |align="center"|Soyuz TM-20|3 October 199422:42:30 |~166 days |22 March 199504:04:05 | Aleksandr Viktorenko Yelena Kondakova Ulf Merbold

|Delivered the EO-17 crew to Mir, in addition to the German Euromir '94 mission. Merbold returned to Earth aboard Soyuz TM-19 after 32 days. |- ! scope="row" |21. |align="center"|Soyuz TM-21|14 March 199506:11:34 |~179 days |06:52:40 | Vladimir Dezhurov Gennady Strekalov Norman E. Thagard| | |Delivered the EO-18 crew to Mir, including Thagard, flying the first US long-duration mission of the Shuttle-Mir programme. The entire crew returned to Earth aboard at the conclusion of STS-71. |- ! scope="row" |22. |align="center"|STS-71|27 June 1995 |4 days, 22 hours | | Robert L. Gibson Charles J. Precourt Ellen S. Baker Bonnie J. Dunbar Gregory J. Harbaugh Anatoly Solovyev Nikolai Budarin| | |Delivered Mir EO-19 crew Returned Mir EO-18 crew |- ! scope="row" |23. |align="center"|Soyuz TM-22|3 September 199509:00:23 |~177 days |29 February 199610:42:08 | Yuri Gidzenko Sergei Avdeyev Thomas Reiter| | |Delivered the EO-20 crew to Mir, including the German Euromir '95 mission. |- ! scope="row" |24. |align="center"|STS-74|12 November 1995 |3 days, 2 hours | | Kenneth D. Cameron James D. Halsell Jerry L. Ross William S. McArthur Chris A. Hadfield

|Delivered Mir Docking Module & Solar Array Package |- ! scope="row" |25. |align="center"|Soyuz TM-23|21 February 199612:34:05 |~192 days |2 September 199607:41:40 | Yuri Onufrienko Yury Usachev| | |Delivered the EO-21 crew to Mir. |- ! scope="row" |26. |align="center"|STS-76|22 March 1996 |4 days, 23 hours | | Kevin P. Chilton Richard A. Searfoss Linda M. Godwin Michael R. Clifford Ronald M. Sega Shannon W. Lucid| | |Delivered Lucid for Mir EO-21 crew Deployed MEEP 1 spacewalk |- ! scope="row" |27. |align="center"|Soyuz TM-24|17 August 199613:18:03 |~195 days |2 March 199706:44:16 | Valery Korzun Aleksandr Kaleri Claudie Haigneré

|Delivered the EO-21 crew to Mir. Haigneré returned to Earth aboard Soyuz TM-23 after 16 days. |- ! scope="row" |28. |align="center"|STS-79| |4 days, 22 hours | | William F. Readdy Terrence W. Wilcutt Thomas D. Akers Jerome Apt Carl E. Walz John E. Blaha| | |Delivered Blaha for Mir EO-22 crew |- ! scope="row" |29. |align="center"|STS-81|12 January 1997 |4 days, 22 hours | | Michael A. Baker Brent W. Jett John M. Grunsfeld Marsha S. Ivins Peter J. K. Wisoff Jerry M. Linenger| | |Delivered Linenger for Mir EO-22 crew |- ! scope="row" |30. |align="center"|Soyuz TM-25|10 February 199714:09:30 |~183 days |14 August 199712:17:10 | Vasili Tsibliyev Aleksandr Lazutkin Reinhold Ewald

|Delivered the EO-23 crew to Mir. Ewald returned to Earth aboard Soyuz TM-24 after 20 days. |- ! scope="row" |31. |align="center"|STS-84|15 May 1997 |4 days, 23 hours | | Charles J. Precourt Eileen M. Collins Carlos I. Noriega Edward T. Lu Jean-François Clervoy Yelena Kondakova Michael Foale| | |Delivered Foale for Mir EO-23 crew |- ! scope="row" |32. |align="center"|Soyuz TM-26|5 August 199715:35:54 |~196 days |19 February 199809:10:30 | Anatoly Solovyev Pavel Vinogradov| | |Delivered the EO-24 crew to Mir. |- ! scope="row" |33. |align="center"|STS-86|27 September 1997 |5 days, 22 hours | | James D. Wetherbee Michael J. Bloomfield Scott E. Parazynski Wendy B. Lawrence Jean-Loup Chrétien Vladimir Titov David A. Wolf| | |Delivered Wolf for Mir EO-24 crew Retrieved MEEP 1 spacewalk |- ! scope="row" |34. |align="center"|STS-89|22 January 1998 |4 days, 21 hours | | Terrence W. Wilcutt Joe F. Edwards Bonnie J. Dunbar Michael P. Anderson James F. Reilly Salizhan Sharipov Andrew S.W. Thomas| | |Delivered Thomas for Mir EO-24 crew |- ! scope="row" rowspan="2"|35. | rowspan="2" align="center" |Soyuz TM-27| rowspan="2" | 29 January 199816:33:42 | rowspan="2" | ~206 days | rowspan="2" | 25 August 199805:24:44 | Talgat Musabayev Nikolai Budarin| rowspan="2" | | | Delivered the EO-25 crew to Mir. |- | Léopold Eyharts | | Eyharts returned to Earth aboard Soyuz TM-26 after 22 days. |- ! scope="row" |36. |align="center"|STS-91|2 June 1998 |3 days, 23 hours | | Charles J. Precourt Dominic L. Pudwill Gorie Wendy B. Lawrence Franklin R. Chang-Diaz Janet L. Kavandi Valery Ryumin

|Returned Thomas from Mir EO-25 crew |- ! scope="row" |37. |align="center"|Soyuz TM-28|13 August 199809:43:11 |~196 days |28 February 199902:14:30 | Gennady Padalka Sergei Avdeyev Yuri Baturin