Ghafour is an Arabic surname. Notable people with this surname include:
Abdul Ghafour (Taliban commander), Taliban commander Amir Ghafour (born 1991), Iranian volleyball player Emad El-Din Abdel-Ghafour, Egyptian politician and co-founder of the Salafist Islamist Homeland Party Hamida Ghafour, Canadian journalist and author of Afghan origin Reham Abdel Ghafour (born 1978), Egyptian actress and daughter of the Egyptian actor Ashraf Abdel Ghafour Sabi Jahn Abdul Ghafour (1969–2004), Afghan prisoner of the Guantanamo Bay detainment camps