This is a list of the Anglo number-one songs of 2016 in Panama. The charts are published by Monitor Latino, based exclusively for English-language songs on airplay across radio stations in Panama using the Radio Tracking Data, LLC in real time. The chart week runs from Monday to Sunday.

Chart history Issue dateSongArtistReference5 December"One Dance" Drake featuring Wizkid and Kyla12 December"Let Me Love You" DJ Snake featuring Justin Bieber19 December"One Dance" Drake featuring Wizkid and Kyla26 December"Work" Rihanna featuring Drake

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